The glioma volume ranges from 5.1633 to 208.165 cm 2. We adopted the surface-based morphometry to investigate the difference of cortical and subcortical gray matter (GM) volumes in a cohort of 14 healthy controls and 13 patients with left-hemisphere cerebral gliomas. The compensation mechanism following contralateral cortical and subcortical structural plasticity is considered. In this study, we aimed to investigate whether the contralateral cortical and subcortical structures are able to actively reorganize by themselves in these patients.
Although numerous non-invasive functional neuroimaging methods have extensively investigated the mechanisms of this functional redistribution in patients with cerebral gliomas, little effort has been made to investigate the structural plasticity of cortical and subcortical structures associated with the glioma volume. Postlesional plasticity has been identified in patients with cerebral gliomas by inducing a large functional reshaping of brain networks. 4Psychological Department, Guangzhou First People’s Hospital, Guangzhou, China.3Neurosurgery, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou, China.
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